EXOME-Horizon™

EXOME- Horizon™ is an integrated system for bio-informatics. It has bio-informatics software suites required by high-end biological research labs. From suites for large genome analysis, to automated drug design, EXOME-Horizon™ is the one stop solution for all your bio-computing needs. The package combines the robust Linux platform with customized, high performance hardware to facilitate efficient analysis of large amounts of data.

The tool is an enhanced and customized distribution of Fedora (A Linux distribution) for bio-informatics research and education. In addition, it includes the capability to adapt to HPC (High Power computing) requirements and contains all major bioinformatics software. EXOME- Horizon™ uses client server architecture, which means that while the databases etc. run on a Linux server, multiple users can access the tools and databases, from either Linux or Windows machines.

EXOME- Horizon™ contains hundreds of bioinformatics programs and software, which can be broadly classified in the following manner:

Features available:

• Genome sequence assembly and sequence cleanup programs
• Genome annotation: Includes gene finding, gene features annotation etc.
• Miscellaneous programs for nucleotide sequence analysis
• Genome comparison and sequence alignment
• Micro-array analysis
• BLAST and related programs
• Phylogenetic and evolution analysis
• Protein sequence analysis
• Protein structure prediction and visualization
• IMD simulations and scalable molecular dynamics
• Small and large bio-molecules analysis and automated docking
• 2D structure prediction
• Fold prediction
• 3D structure prediction (Homology Modeling)
• Energy minimization programs
• Docking
• Small molecules library, PDB, QSAR
• Covers almost the whole bio-informatics application space
• Catering to multiple users simultaneously
• Interactive GUI’s for each program
• Multiple pipelines for diverse bio-informatics experiments
• Project space management; secure data sharing and individual data security
• Customized hardware for high performance

EXOME- Horizon™ has been designed in such way that it can be customized for individual client requirements. The following customisations can be carried out on EXOME- Horizon™:

Customization Scope:

• Graphical visualizations of results.
• Flat file index database system.
• Customizable design according to client requirement.

• Scalable Performance: EXOME- Horizon™ can be customized to work in a parallel computing environment with Ethernet-MPI based components.
• MPI-BLAST can be incorporated into EXOME- Horizon™ , to search large databases in a distributed computing environment.
• Database Installations: all major databases like NCBI, Swissprot, PDB etc can be installed as stand alone databases with search and retrieval systems.